Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.
نویسندگان
چکیده
منابع مشابه
NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation
Structural analysis of the promoters of several endothelial genes induced at sites of inflammatory or immune responses reveals binding sites for the transcription factor nuclear factor kappa B (NF-kappa B). Endothelial cells express transcripts encoding the p50/p105 and p65 components of NF-kappa B and the rel-related proto-oncogene c-rel; steady state levels of these transcripts are transientl...
متن کاملKappa Phi Kappa Pledges Eleven
The election of a queen to preside over junior prom Friday, February 22, from 9:00 to 2 :()(> ./clock at the Aurania club, South Allen street, will be concluded this morning after assembly in the auditorium of Page lull, according to Edward Kramer, vice-president of the junior class and general chairman of the weekend activities. The services of Eric Peterson and bis orchestra have been secured...
متن کاملHyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages
Macrophages play an important role in the acute tissue inflammatory response through the release of cytokines and growth factors in response to stimuli such as lipopolysaccharide (LPS). Macrophage inflammatory effector functions are also influenced by interactions with the extracellular matrix (ECM). Such macrophage-ECM interactions may be important in regulating chronic inflammatory responses....
متن کاملNoise-induced oscillatory shuttling of NF-{\kappa}B in a two compartment IKK-NF-{\kappa}B-I{\kappa}B-A20 signaling model
NF-κB is a pleiotropic protein whose nucleo-cytoplasmic trafficking is tightly regulated by multiple negative feedback loops embedded in the NF-κB signaling network and contributes to diverse gene expression profiles important in immune cell differentiation, cell apoptosis, and innate immunity. The intracellular signaling processes and their control mechanisms, however, are susceptible to both ...
متن کاملInhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression
We report here that both kappa B-dependent transactivation of a reporter gene and NF-kappa B activation in response to tumor necrosis factor (TNF alpha) or H2O2 treatments are deficient in human T47D cell transfectants that overexpress seleno-glutathione peroxidase (GSHPx). These cells feature low reactive oxygen species (ROS) levels and decreased intracellular ROS burst in response to TNF alph...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes & Development
سال: 1995
ISSN: 0890-9369
DOI: 10.1101/gad.9.22.2723